ALOHA
(Allele-frequency/Loss-of-heterozygosity/Allele-imbalance)
INTRODUCTION: ALOHA written in R and R GUI is a tool for a genome-wide
analysis of allele frequency, detection of loss of heterozygosity and identification of allelic imbalance. Moreover, chromosome-wise allele
frequency biplots are provided for
sample classification, outlier detection and SNP clustering.
If publications are based on the results
from the use of ALOHA, please cite the following reference:
Hsin-Chou Yang*, Hsin-Chi Lin, Mei-Chu Huang, Ling-Hui Li, Wen-Harn Pan, Jer-Yuarn Wu, and Yuan-Tsong
Chen (2010). A new analysis tool for individual-level allele frequency for
genomic studies. BMC Genomics 11: 415. (http://www.biomedcentral.com/1471-2164/11/415)
*Correspondence:
Hsin-Chou Yang (hsinchou@stat.sinica.edu.tw), Institute of Statistical Science, Academia Sinica, 128, Academia Road,
Section 2 Nankang, Taipei 115, Taiwan.
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Download
ALOHA:
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VERSION
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DOWNLOAD LINKS
|
FILE TYPE
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FILE SIZE
|
UPDATE
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ALOHA 1.2
|
Software
|
ZIP
|
107 MB*
|
2012-01-01
|
|
|
User guide
|
DOC
|
686 KB
|
2012-01-01
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|
ALOHA 1.1
|
Software
|
ZIP
|
182 MB*
|
2010-07-28
|
|
|
User
guide
|
DOC
|
496 KB
|
2010-07-28
|
|
ALOHA 1.0
|
Software
|
ZIP
|
146 MB*
|
2010-05-16
|
|
|
User
guide
|
DOC
|
527 KB
|
2010-05-16
|
* ALOHA
provides various databases and two test examples. Therefore, the file is
somewhat large!
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Download
program R:
o
R language
(46.4 MB)