BIASLESS (Biomarkers Identification and Samples Subdivision)

 

 

Introduction:

BIASLESS written in R and R-GUI was developed as a user-friendly tool for classification of individuals from different populations/groups based on high-dimensional genomic and transcriptomic marker data. BIASLESS integrates forward variable selection and cross-validation procedures with flexible discriminant analysis to select key predictive markers from enormous numbers of single nucleotide polymorphism (SNP) and/or gene expression (GE) markers. The selected informative markers can be used to classify samples into populations/groups with the highest cross-validation prediction accuracy.

 

Contact:

Please kindly acknowledge if you have downloaded BIASLESS. We will inform you the update of BIASLESS. Any questions, comments and suggestions on BIASLESS are welcome. Please send your feedback to hsinchou@stat.sinica.edu.tw.

 

Citation:

Hsin-Chou Yang*, Pei-Li Wang, Chien-Wei Lin, Chien-Hsiun Chen, and Chun-Houh Chen. (2012) Integrative analysis of single nucleotide polymorphisms and gene expression efficiently distinguishes samples from closely related ethnic populations. BMC Genomics 13, 346. (http://www.biomedcentral.com/1471-2164/13/346/abstract)

 

Download:

VERSION

DOWNLOAD LINKS

FILE TYPE

FILE SIZE

UPDATE

BIASLESS 1.0

Software

ZIP

 3.2 MB

2012-02-18

 

User guide

PDF

 470 KB

2012-02-18

 

BIASLESS must be executed under the environment of R, a free public-domain package. Please download R package here (R-2.15.0-win.exe) or from the website of CRAN (http://cran.csie.ntu.edu.tw/) before executing BIASLESS.