Welcome to the SMART website

SMART (Statistical Metabolomics Analysis - An R Tool)

     Introduction:

SMART written in R and R GUI has been developed as user-friendly software for integrated analysis of metabolomics data. SMART streamlines the complete analysis flow from initial data preprocessing to downstream association analysis, including analyzing different data file formats (e.g., .raw, .d, and mzXML), visually representing various types of data features (e.g., total ion chromatogram and mass spectra), implementing peak alignment, conducting quality control for samples and peaks, exploring batch effects (e.g., known experimental conditions, unknown latent groups, or hidden substructures), and performing association analysis.

     Software:

Version

System

Download File

File Type

File Size

Update Time

SMART 1.2 (beta) Windows (64-bit) $描述: 描述: 描述: 描述: 描述: Z:\genetics\pooledDNA\rar_icon.jpg$
7z

1.75 MB

2019/Mar/27

SMART 1.1

Windows (32-bit)

$描述: 描述: 描述: 描述: 描述: Z:\genetics\pooledDNA\rar_icon.jpg$

7z

75.0 KB

2016/Jul/26

Windows (64-bit)

$描述: 描述: 描述: 描述: 描述: Z:\genetics\pooledDNA\rar_icon.jpg$

7z

79.7 KB

2016/Jul/26

Mac

$描述: 描述: 描述: 描述: 描述: Z:\genetics\pooledDNA\rar_icon.jpg$

7z

48.6 KB

2016/Jul/26

SMART 1.0

Windows (32-bit)

$描述: 描述: 描述: 描述: 描述: Z:\genetics\pooledDNA\rar_icon.jpg$

7z

75.2 KB

2016/May/19

Windows (64-bit)

$描述: 描述: 描述: 描述: 描述: Z:\genetics\pooledDNA\rar_icon.jpg$

7z

79.7 KB

2016/May/19

Mac

$描述: 描述: 描述: 描述: 描述: Z:\genetics\pooledDNA\rar_icon.jpg$

7z

50.1 KB

2016/May/19

·        Other required packages: (1) R language and packages, (2) ActiveTcl 8.5 (32-bit, 64-bit, Mac), and (3) ProteoWizard.

·        Software for unzipping *.7z files can be downloaded from the website: http://www.7-zip.org/

     Example: An antihypertensive pharmacometabolomics study of 5 nonmedication and 5 ACEi medication patients

Version

Description

Download File

File Type

File Size

Update Time

SMART

Raw spectrum files

$描述: 描述: 描述: 描述: 描述: Z:\genetics\pooledDNA\rar_icon.jpg$

7z

853 Mb

2016/May/19

Covariate file

CSV

4 Kb

2016/May/19

Factor file

CSV

4 Kb

2016/May/19

     User guide:

Version

Description

Download File

File Type

File Size

Update Time

SMART 1.2

Instructions

PDF

1.82 Mb

2019/Mar/27

SMART 1.1

Instructions

PDF

2.11 Mb

2016/Jul/26

SMART 1.0

Instructions

PDF

2.11 Mb

2016/May/19

     Citation:

Yu-Jen Liang, Yu-Ting Lin, Chia-Wei Chen, Chien-Wei Lin, Kun-Mao Chao, Wen-Harn Pan and Hsin-Chou Yang (2016/05). SMART: Statistical Metabolomics Analysis – An R Tool. Analytical Chemistry 88, 6334 – 6341.

     Correspondence:

Dr. Hsin-Chou Yang, Institute of Statistical Science, Academia Sinica, 128, Academia Road, Section 2 Nankang, Taipei 115, Taiwan. (Fax) 886-2-27831523; (Tel) 886-2-27889311 ext. 113; (E-mail) hsinchou@stat.sinica.edu.tw